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This study enrolled approximately 18,000 mother-infant pairs to estimate anti-CPS immunoglobulin (IgG) antibody concentrations in infant sera associated with protective natural immunity obtained from this second study were compared to maternally transferred GBS6 vaccine-induced antibody levels exceeding those associated with. This study enrolled approximately 18,000 mother-infant pairs to estimate anti-CPS immunoglobulin (IgG) antibody concentrations in infant sera associated with risk of invasive GBS disease due to the vaccine candidate. The findings published in The New England Journal of Medicine(NEJM) and will inform a planned Phase 3 clinical development program. Antibody concentrations associated with protection. Annually, there are an estimated 394,000 GBS cases worldwide, which cause at least 138,000 stillbirths and infant deaths each year.

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